“The increase of $69.1 million in cash used in operating activities was primarily due to a $48.1 million increase in net loss related to increased costs in research and development, including the overall expansion of our clinical trials for new TIL cell therap…”10-K · Feb 24, 2026 ↗
Iovance Biotherapeutics, Inc.
IOVA
Market read
Iovance Biotherapeutics, Inc.'s current read is isolated; its market group is not confirming.
No new filing conclusion is available. 0 of 16 group members are active now; 0 filing-linked outsiders are moving with the group, and 0 of 20 directly disclosed connections are confirming.
- IOVA's market-adjusted activity becomes unusual and at least one connected name confirms.
Invalidation: The isolated read changes if IOVA's group or a disclosed connection begins moving with it.
Research brief
The story so far
No new filing conclusion is available. 0 of 16 group members are active now; 0 filing-linked outsiders are moving with the group, and 0 of 20 directly disclosed connections are confirming.
No thresholded supportive filing evidence is available yet.
No thresholded adverse filing evidence is available yet.
- IOVA's market-adjusted activity becomes unusual and at least one connected name confirms.
Company research
Understand the business, not just the ticker
Use the company’s filings to identify the few operating, demand, cost, capital and regulatory variables that determine its earnings power.
- Which operating variable is changing?
- Is that change durable, cyclical or one-off?
- What evidence would disprove the current interpretation?
- Latest annual revenue changed +60.6% year over year.
- Operating margin changed +87.8 percentage points in the latest annual period.
- Net margin changed +78.5 percentage points in the latest annual period.
- Diluted shares increased 23.3% in the latest annual period.
- EV/sales is 93% below the available filing-peer median; determine whether growth and quality justify the difference.
Price as of Sep 10, 2026
8.15Reported annual revenue and per-share history. This is accounting history, not a forecast.
What management says matters
Persistent and emerging business drivers
“The increase in cash used of $411.7 million was driven by the $212.6 million payment for the acquisition of the Proleukin ® business, excluding the payment of acquired inventories, which is presented in operating activities, and a $1.9 million increase in cap…”10-K · Feb 24, 2026 ↗
“Expense in 2025 was primarily related to severance payments, costs for outplacement services, and post-employment benefits associated with our August 2025 strategic restructuring plan, resulting from a review of current strategic priorities, the strategic res…”10-K · Feb 24, 2026 ↗
“In addition, to a lesser extent, such costs included period costs incurred for the first few quarters after the launch of Amtagvi ® related to overhead and manufacturing 97 Table of Contents costs at the i CTC during the period from approval resulting from un…”10-K · Feb 24, 2026 ↗
Valuation discipline
Descriptive valuation snapshot
Price/sales 11.1× · EV/sales 10.4×. Comparisons use only industry-matched filing peers.
Fewer than 4 annual revenue periods; too little history to scaffold scenarios.
Price action
How the market is pricing the story
Jodie does not have enough daily observations to draw a useful short-term chart for this asset. The latest quoted price was checked 10 Sept, 15:55 GMT-4; this is a coverage limitation, not a flat-price conclusion.
Developments
No sourced recent-development timeline yet
Jodie has not returned a relevant primary source or news item for IOVA. This is an evidence-coverage gap, not a conclusion that nothing material happened.
Business and financial condition
Reported financial figures are not available yet
Jodie has not returned structured SEC XBRL fundamentals for this asset. This is a coverage limitation, not an assessment of the business or its financial health.
Filing analysis
No comparable filing assessment is available yet
Jodie has not yet found a suitable current-versus-prior filing comparison for IOVA. This does not mean the latest filing was neutral or immaterial.
Business ecosystem
The relationships behind IOVA
Customers, suppliers, partners and competitors named in company filings—not inferred from headlines.
Depends on
FROFrontline plcpartnerAug 7, 2025 ▾
“Through ongoing academic collaborations, as well as government and other partners, we are investigating the next frontier for TIL cell therapy in other tumor types and treatment settings.”
JEFJefferies Financial Group Inc.partnerNov 6, 2025 ▾
“On June 16, 2023, we entered into a new Open Market Sale Agreement, or the 2023 Sale Agreement, with Jefferies with respect to an “at the market” offering program.”
Depended on by
CRSPCRISPR Therapeutics AGcompetitorFeb 12, 2026 ▾
“These competitors are developing ex vivo CAR T therapies, in vivo CAR T therapies, and stem cell-derived cell therapies and include Allogene, Autolus, BlueRock Therapeutics (acquired by Bayer in 2019), Bristol Myers Squibb, Caribou Biosciences, Cellectis, Fat…”
Filing peers
Companies whose filings use similar operating language.
Open the three relationships above to see Jodie’s filing proof. Pro unlocks 24 more links, every receipt, and alerts when connected names begin moving. Unlock the full network →
What is moving around it
Live connections
IOVA is currently a Follower in the organic co-movement group Regional Banks & Financials. This group is discovered from market behaviour rather than assigned from an industry taxonomy. 3 filing-linked names are in the relationship map; none is currently confirmed as moving with the group.
This group is retained as the last observed read for IOVA; it is not active in the latest market snapshot.
Context history
Theme membership history
No durable theme membership has been observed for this name yet.